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An Explorative Study of Haemostasis in Canine Steroid-Responsive Meningitis-Arteritis Using Viscoelastic Monitoring
Kine Bergum Hjellegjerde1, Berry Wong1, Sophie Wyatt2
1Anderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Lane, Hursley, Winchester SO21 2LL, UK.
Animals : an Open Access Journal From MDPI
|January 10, 2026
Summary
Canine steroid-responsive meningitis-arteritis (SRMA) can affect blood clotting. This study used viscoelastic monitoring to assess haemostasis in SRMA-affected dogs, finding potential hypercoagulability and hyperfibrinolysis.
Area of Science:
- Veterinary Neurology
- Immunology
- Haematology
Background:
- Canine steroid-responsive meningitis-arteritis (SRMA) is an immune-mediated inflammatory disease.
- SRMA can lead to central nervous system haemorrhage.
- Haemostatic profiles in SRMA dogs are not well understood.
Purpose of the Study:
- To assess haemostatic function in dogs with SRMA.
- To utilize viscoelastic monitoring for haemostasis evaluation.
- To investigate potential complications in SRMA patients.
Main Methods:
- A multicentre prospective study involving 20 dogs with SRMA.
- Utilized the Entegrion VCM (Viscoelastic Coagulation Monitor) Vet™ device.
- Collected data from four UK veterinary referral hospitals.
Main Results:
- One dog showed hypercoagulable VCM results.
- Two dogs exhibited hyperfibrinolytic VCM results.
- No dogs presented with clinical signs of vascular complications.
Conclusions:
- Viscoelastic monitoring can detect haemostatic abnormalities in SRMA.
- Further research into the fibrinolytic system and endothelial structure in SRMA is needed.
- The pathophysiology of vascular events in SRMA requires further investigation.
