Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Phosphorus Cycle01:21

The Phosphorus Cycle

43.6K
Unlike carbon, water, and nitrogen, phosphorus is not present in the atmosphere as a gas. Instead, most phosphorus in the ecosystem exists as compounds, such as phosphate ions (PO43-), found in soil, water, sediment and rocks. Phosphorus is often a limiting nutrient (i.e., in short supply). Consequently, phosphorus is added to most agricultural fertilizers, which can cause environmental problems related to runoff in aquatic ecosystems.
43.6K
Roles of Electrolytes: Calcium and Phosphate01:27

Roles of Electrolytes: Calcium and Phosphate

1.1K
Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily...
1.1K
Introduction to Electrolytes01:33

Introduction to Electrolytes

15.1K
In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
Role of Sodium
One...
15.1K
Phosphorylation01:02

Phosphorylation

53.6K
The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...
53.6K
Protein Kinases and Phosphatases02:54

Protein Kinases and Phosphatases

14.9K
Proteins undergo chemical modifications that trigger changes in the charge, structure, and conformation of the proteins. Phosphorylation, acetylation, glycosylation, nitrosylation, ubiquitination, lipidation, methylation, and proteolysis are various protein modifications that regulate protein activity. Such modifications are usually enzyme-driven.
Protein kinases
Many proteins in the cell are regulated by phosphorylation, the addition of a phosphate group. A family of enzymes called kinases...
14.9K
The Parathyroid Glands00:59

The Parathyroid Glands

4.3K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A preliminary study through lymphocyte immunophenotyping of the effects of different forms of phosphorus deficiency on dairy cattle blood haematological parameters and immune status.

Journal of veterinary research·2025
Same author

Lameness in Cattle-Etiopathogenesis, Prevention and Treatment.

Animals : an open access journal from MDPI·2024
Same author

Basal Intestinal Morphology, Immunolocalization of Leptin and Ghrelin and Their Receptors in Newborn Wistar Rats after Prenatal Exposure to Fumonisins.

Animals : an open access journal from MDPI·2023
Same author

Body balance in people practicing snowboarding.

Acta of bioengineering and biomechanics·2019
Same author

Epidemiology of human trichinellosis in Vojvodina province, Serbia, from 2005 to 2016.

Acta veterinaria Hungarica·2019
Same author

Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency.

International journal of endocrinology·2016

Related Experiment Video

Updated: Jan 13, 2026

High-Throughput Measurement and Classification of Organic P in Environmental Samples
08:58

High-Throughput Measurement and Classification of Organic P in Environmental Samples

Published on: June 8, 2011

13.4K

Phosphorus Metabolism and Function in Ruminants: Current Knowledge.

Beata Abramowicz1, Ewa Tomaszewska2, Oliwia Brzezińska1

  • 1Department and Clinic of Animal Internal Diseases, University of Life Sciences in Lublin, Akademicka 13, 20-912 Lublin, Poland.

Animals : an Open Access Journal From MDPI
|January 10, 2026
PubMed
Summary

Phosphorus deficiency in dairy cows impacts milk yield, immunity, and muscle function. Optimal phosphorus nutrition is vital for cow health, productivity, and minimizing environmental phosphorus loss.

Keywords:
FGF23acute-phase proteinsdairy cowsmineral metabolismphosphorus deficiencypostpartum disorders

More Related Videos

Measuring Phosphorus Release in Laboratory Microcosms for Water Quality Assessment
06:42

Measuring Phosphorus Release in Laboratory Microcosms for Water Quality Assessment

Published on: July 22, 2019

7.0K
Assaying for Inorganic Polyphosphate in Bacteria
07:20

Assaying for Inorganic Polyphosphate in Bacteria

Published on: January 21, 2019

9.2K

Related Experiment Videos

Last Updated: Jan 13, 2026

High-Throughput Measurement and Classification of Organic P in Environmental Samples
08:58

High-Throughput Measurement and Classification of Organic P in Environmental Samples

Published on: June 8, 2011

13.4K
Measuring Phosphorus Release in Laboratory Microcosms for Water Quality Assessment
06:42

Measuring Phosphorus Release in Laboratory Microcosms for Water Quality Assessment

Published on: July 22, 2019

7.0K
Assaying for Inorganic Polyphosphate in Bacteria
07:20

Assaying for Inorganic Polyphosphate in Bacteria

Published on: January 21, 2019

9.2K

Area of Science:

  • Ruminant Nutrition and Metabolism
  • Dairy Cattle Physiology
  • Mineral Homeostasis

Background:

  • Phosphorus (P) is a critical macromineral for dairy cattle, involved in energy metabolism, skeletal health, and cellular signaling.
  • Its homeostasis is regulated by parathyroid hormone, calcitriol, and fibroblast growth factor 23 (FGF23).
  • Phosphorus deficiency frequently occurs during the transition period, leading to decreased milk production and health issues.

Purpose of the Study:

  • To review phosphorus metabolism in ruminants, highlighting species-specific differences.
  • To detail the hormonal regulation of phosphorus homeostasis.
  • To discuss clinical signs of deficiency, diagnostic approaches, and impacts on immunity and the environment.

Main Methods:

  • Literature review of phosphorus metabolism in ruminants.
  • Analysis of hormonal regulation and FGF23 physiology.
  • Examination of clinical manifestations and diagnostic methods.

Main Results:

  • Phosphorus deficiency causes reduced milk yield, anemia, muscle weakness, and immunosuppression.
  • Postpartum hypophosphatemia is linked to acute-phase proteins, postpartum hemoglobinuria, and recumbency.
  • Phosphorus imbalance affects periparturient immune function and increases environmental phosphorus excretion.

Conclusions:

  • Optimal phosphorus nutrition is essential for dairy cow health and productivity.
  • Understanding phosphorus metabolism aids in preventing deficiency-related disorders.
  • Managing phosphorus intake reduces environmental impact and improves animal welfare.