Supervised 16-Week Multicomponent Exercise Training Programme for 18-55-Year-Old People Living with and Beyond...

Despite evidence that exercise improves treatment outcomes, most people living with and beyond cancer (PLWBC) are insufficiently physically active. To address this challenge the Onco-Move Improvement of psychophysical fitness in adult cancer survivors pilot randomized controlled trial aims to investigate the 7-month effects of a 16-week supervised, multicomponent exercise programme on PLWBC adults aged 18-55. The study will include 40 participants currently undergoing cancer treatment or up to 5 years post-treatment with different types of cancer, who will be randomly assigned to the experimental or the control group. The exercise programme will take place three times a week for 16 weeks. We hypothesize that the Onco-Move exercise programme will improve participants' quality of life, sexual function, and stress-response strategies, as well as their nutrition, physical functions, and body composition. We also expect to observe physiological changes related to the intervention influencing inflammation, metabolism, muscle adaptation, and cellular aging. The Onco-Move exercise programme, once validated, has the potential to be implemented in oncological non-governmental organizations (NGOs) and hospitals in Poland and Spain, among others, as a feasible, effective, and safe non-pharmacological aid for cancer patients and survivors.