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Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and

Shooka Mohammadi1, Damoon Ashtary-Larky2, Mahsa Erfanian-Salim3

  • 1Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

Nutrients
|January 10, 2026
PubMed
Summary

Melatonin supplementation significantly improves multiple cardiometabolic risk factors (CMRFs), including blood pressure and cholesterol levels. However, it does not impact body weight or insulin resistance markers.

Keywords:
blood pressurecardiometabolic risksglycemic controlinflammationlipid profilemelatoninoxidative stress

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