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Association Between Fibromyalgia and Risk of Developing Sarcopenia According SARC-F: A Cross-Sectional Study.
Blanca Pedauyé-Rueda1,2, Eduardo Cimadevilla Fernández-Pola1,2, Hilin Hussein1
1Physiotherapy and Health Research Group (FYSA), Department of Physiotherapy, HM Faculty of Health Sciences, Camilo José Cela University, 28692 Madrid, Spain.
Diagnostics (Basel, Switzerland)
|January 10, 2026
Summary
Fibromyalgia (FM) patients show a high risk of sarcopenia, a condition involving muscle mass loss. This study highlights a significant link between FM
Area of Science:
- Gerontology
- Rheumatology
- Neurology
Background:
- Fibromyalgia (FM) is a chronic pain condition, potentially with muscular stiffness.
- Sarcopenia is characterized by progressive loss of muscle mass and strength.
- Muscle mass loss is a critical factor in the progression of both FM and sarcopenia.
Purpose of the Study:
- To investigate the association between fibromyalgia and an elevated risk of developing sarcopenia.
Main Methods:
- 84 fibromyalgia patients were assessed for sociodemographics, anthropometrics (circumferential and ultrasound), pain (VAS and algometry), sarcopenia risk (SARC-F), sleep quality, anxiety, and depression.
Main Results:
- 56.3% of participants had a high risk of sarcopenia (SARC-F).
- Fibromyalgia Impact Questionnaire (FIQ) scores significantly correlated with sleep quality and depression.
- High sarcopenia risk (SARC-F) was significantly associated with FIQ scores and depression.
Conclusions:
- A significant association exists between fibromyalgia impact and a high risk of sarcopenia (SARC-F).
- Fibromyalgia patients in this study reported high pain levels, significantly linked to increased anxiety and depression.

