Related Experiment Video
Updated: Jan 13, 2026

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Factors Associated with Pressure Injury Occurrence in Older Trauma Patients
1Department of Trauma Surgery, Incheon Regional Trauma Center, Gachon University Gil Medical Center, 21 Namdong-daero, Yeonsu-gu, Incheon 21565, Republic of Korea.
Abstract:
Background/Objectives: Older individuals are more vulnerable to stress and trauma. Although pressure injuries (PIs) are recognized as a significant complication, the specific impact of frailty on PI development in older Asian trauma patients remains insufficiently explored. This study aims to investigate the factors associated with the occurrence of hospital-acquired pressure injuries (HAPU) in older patients aged ≥65 years, including frailty. Methods: This study is a retrospective secondary data analysis of 3418 older trauma patients admitted to a regional trauma center (including ICU and trauma ward) from 1 January 2020 to 31 December 2023. Patients with PIs present on admission (POA) were excluded to strictly analyze new PI occurrence. Frailty was assessed using the mFI-5. Results: The mean age of participants was 77.33 years. During hospitalization, 2.5% (n = 84) of patients developed new PIs. Multivariate logistic regression identified that higher frailty score (Odds Ratio [OR] = 1.59, 95% Confidence Interval [CI]: 1.26-2.02), lower BMI (OR = 0.93, 95% CI: 0.86-0.99), hypoalbuminemia (OR = 0.55, 95% CI: 0.36-0.84), and prolonged hospital stay (OR = 1.05, 95% CI: 1.04-1.06) were independently associated with PI occurrence. Chronological age was not a significant predictor in the multivariate model. Conclusions: Frailty, nutritional status (BMI, albumin), and prolonged hospital stay are significant factors associated with HAPU in older trauma patients.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacodynamics in Geriatric Patients: Effects of Age
The Effect of Aging on Tissues
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Factors affecting Blood pressure
Physiological Factors:
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

