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Updated: Jan 13, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
PomBase in 2026: expanding knowledge, modeling connections
Pascal Carme1,2, Kim Rutherford1, Jürg Bähler2
1Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
None:
PomBase is the model organism database dedicated to the fission yeast Schizosaccharomyces pombe. In this update, we outline recent progress in literature curation, the introduction of new tools, and enhancements designed to better support the research community. We highlight our recent effort to curate biological pathways and modules as causal networks using Gene Ontology-Causal Activity Modelling and describe new features that utilize these models to guide and inform hypothesis-driven research.
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