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Updated: Jan 13, 2026
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Maternal electrocardiographic and hemodynamic parameters in fetal growth restriction: a case control study
Burcu Bozkurt Ozdal1, Ayse Seval Ozgu-Erdınc1, Nursen Ozen2
1Republic of Turkey Ministry of Health Ankara City Hospital, Department of Perinatology, Turkey.
Aim:
This study investigates relationships between maternal ECG parameters, blood pressure, and FGR, and evaluates their potential as FGR predictors.
Materials And Methods:
A case-control study was performed between April and July 2025. We enrolled 183 pregnant women (32-37 weeks): 68 with FGR and 115 controls. Maternal demographic, clinical, ECG, and blood pressure data were collected and analyzed.
Results:
FGR mothers had lower heart rates, longer QTc and PR intervals, higher RR intervals, and higher systolic and diastolic blood pressures than controls (p < 0.05). QTc, SBP, DBP, MAP, and FGR were positively correlated. Regression analysis found that prolonged QTc and higher systolic blood pressure were significantly associated with FGR risk. ROC analysis yielded moderate sensitivity and specificity for QTc (413 ms), heart rate (81.5 bpm), SBP (110.5 mmHg), and DBP (61.0 mmHg).
Conclusion:
Our results show exploratory associations between maternal ECG/blood pressure markers and FGR at 32-37 weeks in a single center. With modest predictive value (AUC 0.64-0.73), these findings do not yet justify clinical screening use. Multicenter studies are needed for validation.
