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Updated: Jan 13, 2026

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Next-generation sequencing as an applicable method: from technical basis to use in medical diagnosis

Arman Moradi1, Mina Mousavi2, Majid Maleki3

  • 1Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.

Gene
|January 10, 2026
PubMed
Summary

Next-generation sequencing (NGS) offers economical genetic diagnosis and screening from prenatal stages through lifespan. This technology enhances personalized medicine, pharmacogenetics, and precise genome editing, improving patient quality of life.

Keywords:
Next generation sequencingPersonalized medicinePharmacogeneticsWhole exome sequencing

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