A visual reinterpretation of the 2024 McDonald criteria for multiple scleroris

The 2024 revision of the McDonald criteria for multiple sclerosis (MS) has recently been published. This update introduces several important advances aimed at achieving an earlier and more specific diagnosis, particularly through the inclusion of new biomarkers and neuroimaging findings. However, while the criteria have become more comprehensive, their complexity and practical application have also increased. We therefore propose a visual reinterpretation of the 2024 McDonald criteria, presented as a point-based schematic, to facilitate their interpretation. In this model, a total score of four points or higher supports the diagnosis of MS, provided that no better explanation exists. We believe that this visual approach may enhance understanding and applicability of the new criteria, especially among non-specialists in neuroimmunology and neurology trainees.