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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
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The Argentinian Crohn's Disease and Ulcerative Colitis Registry (RADECCU): Methodological aspects and objectives.

Domingo Balderramo1, Joaquín Montero2, Juan Lasa3

  • 1Gastroenterology Department, Hospital Privado Universitario de Córdoba, Instituto Universitario de Ciencias Biomédicas de Córdoba, Córdoba, Argentina.

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Summary

The first national Inflammatory Bowel Disease (IBD) registry in Argentina, RADECCU, was established in 2023. It aims to collect crucial data on Crohn's disease and ulcerative colitis patients nationwide.

Keywords:
ArgentinaColitis ulcerosaCrohn's diseaseEnfermedad de CrohnEnfermedad inflamatoria intestinalEpidemiologyEpidemiologíaInflammatory bowel diseaseRegistroRegistryUlcerative colitis

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Area of Science:

  • Gastroenterology and Hepatology
  • Epidemiology
  • Clinical Research

Background:

  • Limited national-level data exists for Inflammatory Bowel Disease (IBD) in Argentina.
  • Need for a centralized system to gather comprehensive information on IBD patients in the country.

Purpose of the Study:

  • To describe the methodology and establishment of the Argentine Registry of Crohn's Disease and Ulcerative Colitis (RADECCU).
  • To lay the foundation for collecting relevant patient information for IBD in Argentina.

Main Methods:

  • The RADECCU registry platform was developed in January 2023.
  • A national promotional campaign was conducted to encourage center participation.
  • Data collection commenced following platform development and center recruitment.

Main Results:

  • By June 2025, 69 centers (41 private, 28 public) joined the RADECCU registry.
  • A total of 142 healthcare professionals were incorporated.
  • The registry enrolled 4,081 patients (2,275 women, 1,806 men) with IBD.

Conclusions:

  • RADECCU represents the first national registry for IBD in Argentina.
  • The registry is poised to offer insights into the IBD landscape in Argentina.
  • It has the potential to contribute valuable real-world evidence to Latin American IBD data.