Related Experiment Video

Updated: Jan 13, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

3.5K

Pregnancy, Birth, Neonatal, and Mental Health Outcomes Are Minimally Associated with Pregnancy Ambivalence

Karen Trister Grace, Samantha Auerbach, Amy Alspaugh

    Studies in Family Planning
    |January 12, 2026
    PubMed

    Pregnancy ambivalence is increasingly recognized and studied in sexual and reproductive health research, yet its associations with adverse outcomes remain unclear. The purpose of this paper was to explore different measures of ambivalence and whether any were associated with poor pregnancy, birth, social or mental health outcomes. A cross-sectional survey was conducted with 1941 individuals assigned female at birth, ages 18-45, who had been pregnant in the past 2 years. Ambivalence measures included the London Measure of Unplanned Pregnancy (LMUP) and additional questions exploring mixed feelings, uncertainty, incongruent feelings, and fatalistic beliefs about pregnancy planning. No associations were observed between ambivalence and birth/neonatal outcomes, though ambivalence measures were linked to delayed prenatal care, exposure to harmful behaviors during pregnancy, and increased odds of depression, anxiety, and intimate partner violence. Mental health assessments and intimate partner violence screening could improve care delivery and outcomes more than screening for pregnancy ambivalence. The LMUP, which captures multiple dimensions of ambivalence as well as addresses the deficiencies with traditional measures of behavior, may be the strongest measure to use when needing to comprehensively measure pregnancy ambivalence.

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