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Dental Calculus Deposition: Correlation With Salivary Statherin and Calcium Levels
Pranjali Hase1, Vandana Shah1, Shilpa Gunjal2
1Department of Oral and Maxillofacial Pathology, K M Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, 391760, Gujarat, India, sumandeepuniversity.co.in.
International Journal of Dentistry
|January 12, 2026
Summary
Elevated salivary calcium levels are linked to increased dental calculus formation. Salivary statherin did not show a significant correlation with calculus development or calcium concentration.
Area of Science:
- Oral Biology
- Biochemistry
Background:
- Saliva plays a crucial role in oral calcium homeostasis.
- Salivary proteins like statherin can inhibit calcium phosphate crystal growth.
- Saliva supersaturated with calcium phosphates drives plaque mineralization and calculus formation.
Purpose of the Study:
- To investigate the relationship between salivary statherin and calcium concentrations and dental calculus formation.
- To correlate salivary constituents with the degree of dental calculus deposition.
Main Methods:
- 90 participants (aged 20-40) were categorized into control, low, and high dental calculus index groups.
- Saliva samples were collected from all participants.
- Salivary calcium and statherin levels were quantified and analyzed in relation to the calculus index.
Main Results:
- Salivary calcium levels significantly increased from the control group to the high calculus group (2.221 to 10.072 mg/dL).
- A significant positive correlation was observed between salivary calcium levels and the calculus index (r=0.639, p<0.001).
- Salivary statherin levels showed a non-significant, modest negative correlation with both calcium concentration and calculus index.
Conclusions:
- Salivary calcium concentration is a key factor in dental calculus formation.
- Salivary statherin does not appear to be a significant predictor of calculus development in this study population.
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