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Updated: Jan 13, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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How to Minimize the bias Introduced in Blood Donor's Haemoglobin Due to the Determination Method in Practice with

Priyadarsini Jayachandran Arcot1, Aarushi Sahni2, Karan Kumar1

  • 1Department of Transfusion Medicine & Blood Centre, AIIMS Kalyani, Ghora Gachha , West Bengal 741245 India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|January 12, 2026
PubMed

Estimation of haemoglobin (Hb) plays an important role in the medical examination of prospective blood donors. Various tests to estimate Hb are available in the market to screen for donor Hb with their own set of advantages and disadvantages. Each Blood centre chooses their test based on the availability of funds / resources, manpower and number of donations. Like any other test, Hb estimation tests also have various factors resulting in erroneous results. Identifying and preventing such factors is crucial in maintaining the safety of donor and the patient. This short research communication dwells upon such common factors influencing Hb estimation in the routine blood donor screening and what can be done to prevent such errors.

Keywords:
BiasIndividual donors’ blood managementMeasurement method in practiceMentor measurement methodTrue value of haemoglobin

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