Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

385
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
385
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

456
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
456
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

394
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
394
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

273
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
273
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

237
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
237

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of Inflammation in the Pathophysiology of Heart Failure.

Cells·2025
Same author

The CORolla device for energy transfer from systole to diastole: a novel treatment for heart failure with preserved ejection fraction.

Heart failure reviews·2021
See all related articles

Related Experiment Video

Updated: Jan 13, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

12.2K

Transcatheter Aortic Valve Replacement for Aortic Insufficiency.

Marwan Amara1,2, Yair Feld2

  • 1Cardiology Department, The Baruch Padeh Medical Center (Tzafon) Poriya, TabarÄ«ya, Israel.

Interventional Cardiology (London, England)
|January 12, 2026
PubMed
Summary

Transcatheter aortic valve replacement (TAVR) offers a viable treatment for aortic regurgitation (AR). Newer TAVR devices show improved outcomes and reduced complications for patients with severe AR.

Keywords:
Aortic regurgitationdedicated devicestranscatheter aortic valve replacement

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

3.4K

Related Experiment Videos

Last Updated: Jan 13, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

12.2K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

3.4K

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Transcatheter aortic valve replacement (TAVR) is a key treatment for aortic regurgitation (AR), especially in high-risk patients.
  • Early TAVR devices faced challenges like high mortality and paravalvular leaks.
  • Technological advancements have significantly improved TAVR procedural outcomes.

Purpose of the Study:

  • To review the evolution and current state of TAVR for aortic regurgitation.
  • To highlight advancements in TAVR technology for AR treatment.
  • To discuss the potential of dedicated and novel devices for complex AR cases.

Main Methods:

  • Review of current literature on TAVR for AR.
  • Analysis of outcomes associated with early and advanced TAVR devices.
  • Evaluation of specific TAVR systems designed for AR.

Main Results:

  • Advancements in self-expanding and balloon-expandable TAVR devices have enhanced procedural success.
  • Dedicated AR devices like Trilogy and J-Valve demonstrate superior performance and survival rates.
  • Emerging systems show promise for treating complex AR, including non-calcified valves and endocarditis.

Conclusions:

  • Modern TAVR technology provides effective treatment options for severe aortic regurgitation.
  • Dedicated devices and innovative systems are improving outcomes for AR patients.
  • Tailored TAVR approaches based on patient-specific anatomy and pathology are crucial for optimal results.