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Curative surgery enabled by radiotherapy in rectal cancer: A case report
Sofia E Sánchez-De-Toca1, Fernando Mendoza Moreno1, Patricia Urbón Sánchez1
1Department of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, 28805 Madrid, Spain.
Oncology Letters
|January 12, 2026
Summary
For locally advanced rectal cancer patients ineligible for chemotherapy, radiotherapy alone can enable curative surgery. This case study shows radiotherapy successfully bridged a patient to complete tumor removal when combined treatment was not possible.
Area of Science:
- Oncology
- Surgical Oncology
- Radiation Oncology
Background:
- Neoadjuvant chemoradiotherapy is standard for locally advanced rectal cancer.
- Chemotherapy contraindications, like active infections, limit treatment options.
- Guidelines are scarce for patients unable to receive combined neoadjuvant therapy.
