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Comparative In vitro Analysis of Resorbable vs Titanium Miniplates in Simulated Mandibular Fracture Models.

Rohan Hattarki1, Nikil Kumar Jain2, Vineet Vaibhav3

  • 1Department of Orthodontics and Dentofacial Orthopedics, KLE VK Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, Karnataka, India.

Journal of Pharmacy & Bioallied Sciences
|January 12, 2026
PubMed
Summary

Titanium miniplates offer superior mechanical stability for mandibular fractures compared to resorbable plates. Resorbable systems may be suitable for specific cases, but titanium provides better fracture resistance in load-bearing areas.

Keywords:
Miniplatesresorbabletitaniu

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Biomaterials Engineering
  • Orthopedic Biomechanics

Background:

  • Mandibular fracture management traditionally uses titanium miniplates.
  • Resorbable plating systems present potential benefits like avoiding second-stage surgery.
  • Complications associated with long-term hardware presence are a concern.

Purpose of the Study:

  • To compare the mechanical stability of resorbable versus titanium miniplates.
  • To evaluate fracture resistance in simulated mandibular fractures.
  • To assess performance under standardized in vitro conditions.

Main Methods:

  • Forty synthetic polyurethane mandibles with angle fractures were used.
  • Two groups were established: titanium miniplates (Group A) and resorbable polylactic acid miniplates (Group B).
  • Biomechanical testing measured load to failure and displacement at failure using a universal testing machine.

Main Results:

  • Titanium miniplates demonstrated significantly higher load to failure (295.7 N) than resorbable plates (187.6 N).
  • Displacement at failure was significantly lower with titanium (1.62 mm) compared to resorbable plates (2.38 mm).
  • 15% of resorbable constructs showed screw loosening, while all titanium constructs maintained integrity.

Conclusions:

  • Titanium miniplates provide superior mechanical stability and fracture resistance in simulated mandibular fractures.
  • Resorbable plates may be advantageous in specific patient populations (e.g., pediatric) or selected cases.
  • Caution is advised when using resorbable systems in load-bearing mandibular regions due to mechanical limitations.