A Tertiary Care Hospital's Antimicrobial Sensitivity Pattern and Microorganism Spectrum
Sourabh Kumar Tiwari1, Mansi Gupta1, Neelu Jain1
1Department of Microbiology, Bundelkhand Government Medical College, Sagar, Madhya Pradesh, India.
Background:
Antimicrobial resistance (AMR) is a growing public health threat, especially in tertiary care settings where infection burden is high. Surveillance of pathogen distribution and resistance patterns is crucial for guiding effective empirical therapy.
Objective:
To determine the spectrum of microorganisms isolated from clinical samples and their antimicrobial susceptibility patterns in a tertiary care hospital.
Materials And Methods:
This cross-sectional observational study was conducted over 2 years at the Department of Microbiology, Bundelkhand Government Medical College, Sagar. Various clinical specimens were processed and analyzed using standard microbiological techniques. Antimicrobial susceptibility testing was performed as per CLSI guidelines.
Results:
Out of 4,216 samples, 85.6% showed growth. Escherichia coli was the most common isolate (26.3%), followed by Staphylococcus aureus (17.0%), with 62.3% being MRSA. High levels of MDR and ESBL production were noted among Gram-negative bacteria.
Conclusion:
The study highlights the need for regular antibiogram updates and strict antimicrobial stewardship.
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