Adhesive Property of Different Bonding Agents to Dentin: A Microscopic Study

Bonding agents play a critical role in the longevity and success of restorative dental treatments by minimizing microleakage at the tooth-restoration interface. The evolution from fifth- to eighth-generation bonding systems reflects the ongoing efforts to simplify procedures while improving clinical outcomes.

Sixty extracted human molars were divided into four groups based on the generation of bonding agents used: Fifth (Adper Single Bond 2), sixth (Clearfil SE), seventh (BeautiBond), and eighth (GC Premio Bond). Standardized Class V cavities were prepared and restored. Microleakage was assessed using methylene blue dye under a stereomicroscope.

Eighth-generation bonding agent demonstrated the least microleakage, while the seventh generation showed the most. Statistical analysis confirmed significant differences among the groups (P < 0.05).

The eighth-generation bonding agent showed superior performance in reducing microleakage compared to earlier generations, indicating its potential as the most effective adhesive system.