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A Comparative Assessment of Tooth Movement through an Invasive and Noninvasive Method Using Micro-osteoperforation
Soumya Gupta1, Vivek Soni1, Sameer Narkhede1
1Department of Orthodontics and Dentofacial Orthopedics, D.Y. Patil School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|January 12, 2026
Summary
Combining micro-osteoperforation (MOPs) and low-level laser therapy (LLLT) significantly accelerates canine retraction in bimaxillary protrusion cases. This combined approach enhances tooth movement speed, offering an effective acceleration technique for orthodontic treatment.
Area of Science:
- Orthodontics
- Biomaterials Science
- Dental Technology
Background:
- Bimaxillary protrusion cases often require complex orthodontic treatment.
- Accelerating tooth movement is a key goal in modern orthodontics.
- Micro-osteoperforation (MOPs) and low-level laser therapy (LLLT) are emerging techniques to enhance orthodontic treatment speed.
Purpose of the Study:
- To evaluate the effect of micro-osteoperforation (MOPs) and low-level laser therapy (LLLT) on the rate of canine retraction.
- To compare the efficacy of MOPs, LLLT, and their combination in accelerating tooth movement in bimaxillary protrusion.
- To assess anchorage loss associated with MOPs and LLLT.
Main Methods:
- Eighty maxillary canines were divided into four groups: MOPs, LLLT, combined MOPs and LLLT, and control.
- Canine retraction was achieved using Ni-Ti closed coil springs with a force of 150 g on a stainless steel archwire.
- MOPs were performed every three weeks, and LLLT was applied for 10 seconds at the same intervals for three months.
Main Results:
- The combination of MOPs and LLLT (Group 4) demonstrated a significant 3.02-fold increase in the rate of tooth movement (P = 0.001).
- No significant difference in anchorage loss was observed between the MOPs and LLLT groups.
- LLLT showed a high level of patient satisfaction and procedural ease.
Conclusions:
- The synergistic effect of combining MOPs and LLLT highlights their value as integrated acceleration techniques for orthodontic treatment.
- Combined MOPs and LLLT offer a promising strategy for optimizing outcomes in canine retraction.
- LLLT is a user-friendly and well-tolerated adjunctive therapy.

