Related Experiment Video
Updated: Jan 13, 2026
Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
A Comparative Assessment of Tooth Movement through an Invasive and Noninvasive Method Using Micro-osteoperforation
Soumya Gupta1, Vivek Soni1, Sameer Narkhede1
1Department of Orthodontics and Dentofacial Orthopedics, D.Y. Patil School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Objectives:
To evaluate the effect of the rate of canine retraction by micro-osteoperforation and photobiostimulation in bimaxillary protrusion cases.
Methods:
Eighty maxillary canines were selected as per inclusion criteria and further equally divided into 20 maxillary canines into four groups; in Group 1, Micro-osteoperforation was performed distal to the maxillary canine and was repeated every three weeks for three months. Group 2: Low-level laser therapy (2 W, 810 nm, 4.77 J/cm2) was given for 10 seconds at the same interval as Group 1. Group 3: On the one side Group 1 therapy whereas on the other side Group 2 therapy was delivered. Group 4: It is the combination of both Groups 1 and 2 on the same side and the other side as control. The canine retraction was achieved using a Ni-Ti closed coil spring providing 150 g of force from the canine to the TADs, on a 0.019″ × 0.025″ stainless steel arch wire. The rate of canine retraction was measured.
Results:
The micro-osteoperforation (MOPs) and low-level laser therapy (LLLT) combined with Group 4 showed a significantly increased rate of tooth movement by 3.02-fold (P = 0.001). There was no significant difference in anchorage loss between MOP and LLLT.
Conclusion:
The synergistic effect observed with the combined use of MOP and LLLT underscores the value of integrating acceleration techniques for optimal outcomes. The level of satisfaction and degree of easiness of the procedure were high in LLLT.
