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Fibrinogen superfamily proteins: Key regulators in hepatic disorders

Rong-Hui Qu1, Yi Rong1, Wen-Zhe Ni1

  • 1College of Life Sciences, Shandong Agricultural University, Tai'an 271018, Shandong Province, China.

World Journal of Experimental Medicine
|January 12, 2026
PubMed
Summary

Fibrinogen superfamily proteins regulate liver health, offering protection but also driving disease when overactive. Targeting these proteins, like FGL1, shows promise for treating liver diseases and cancer.

Keywords:
Fibrinogen superfamilyHepatitisHepatocellular carcinomaLiver injuryMetabolic associated fatty liver disease

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