Secondary Prevention Implantable Cardioverter-Defibrillator for Cardiac Arrest Survivors on Hemodialysis in Japan - A

Kosuke Nakasuka1, Yomei Sakurai1, Yu Kawada1

  • 1Department of Cardiology, Nagoya City University Graduate School of Medical Sciences Nagoya Japan.

Circulation Reports
|January 12, 2026
PubMed

Insights

Secondary prevention implantable cardioverter-defibrillator (ICD) use is significantly lower in hemodialysis patients in Japan. Practice patterns showed consistent implantation rates across regions, with increasing subcutaneous-ICD use.

Area of Science:

  • Cardiology
  • Nephrology
  • Medical Device Technology

Background:

  • Secondary prevention implantable cardioverter-defibrillator (ICD) implantation in hemodialysis (HD) patients in Japan is not well understood.
  • Characterizing practice patterns and factors influencing ICD use in HD patients surviving cardiac arrest due to ventricular arrhythmias is crucial.

Purpose of the Study:

  • To characterize the clinical implementation of secondary prevention ICDs in Japanese hemodialysis patients.
  • To identify factors associated with ICD implantation in this population.
  • To analyze trends in device selection and variations in utilization.

Main Methods:

  • Nationwide analysis of the JROAD-DPC database (2012-2020).
  • Inclusion of cardiac arrest survivors with ventricular arrhythmias and no prior ICD.
  • Assessment of patient factors, temporal trends, and institutional/geographical variations in ICD implantation among HD patients.

Main Results:

  • HD patients had significantly lower ICD implantation rates (27%) compared to non-HD patients (44%).
  • Hemodialysis treatment was an independent negative predictor of ICD implantation (OR 0.42).
  • Subcutaneous-ICD use among HD patients increased from 13% to 32% (2016-2019).

Conclusions:

  • Significantly lower secondary prevention ICD use in HD patients compared to non-HD patients was observed.
  • ICD implantation patterns were consistent across Japanese healthcare institutions and regions.
  • Findings highlight the need for consensus development and prospective studies for optimal ICD selection in HD patients.
Abstract

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