Related Experiment Video
Updated: Jan 13, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Secondary Prevention Implantable Cardioverter-Defibrillator for Cardiac Arrest Survivors on Hemodialysis in Japan - A
Kosuke Nakasuka1, Yomei Sakurai1, Yu Kawada1
1Department of Cardiology, Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Insights
Secondary prevention implantable cardioverter-defibrillator (ICD) use is significantly lower in hemodialysis patients in Japan. Practice patterns showed consistent implantation rates across regions, with increasing subcutaneous-ICD use.
Area of Science:
- Cardiology
- Nephrology
- Medical Device Technology
Background:
- Secondary prevention implantable cardioverter-defibrillator (ICD) implantation in hemodialysis (HD) patients in Japan is not well understood.
- Characterizing practice patterns and factors influencing ICD use in HD patients surviving cardiac arrest due to ventricular arrhythmias is crucial.
Purpose of the Study:
- To characterize the clinical implementation of secondary prevention ICDs in Japanese hemodialysis patients.
- To identify factors associated with ICD implantation in this population.
- To analyze trends in device selection and variations in utilization.
Main Methods:
- Nationwide analysis of the JROAD-DPC database (2012-2020).
- Inclusion of cardiac arrest survivors with ventricular arrhythmias and no prior ICD.
- Assessment of patient factors, temporal trends, and institutional/geographical variations in ICD implantation among HD patients.
Main Results:
- HD patients had significantly lower ICD implantation rates (27%) compared to non-HD patients (44%).
- Hemodialysis treatment was an independent negative predictor of ICD implantation (OR 0.42).
- Subcutaneous-ICD use among HD patients increased from 13% to 32% (2016-2019).
Conclusions:
- Significantly lower secondary prevention ICD use in HD patients compared to non-HD patients was observed.
- ICD implantation patterns were consistent across Japanese healthcare institutions and regions.
- Findings highlight the need for consensus development and prospective studies for optimal ICD selection in HD patients.
Background:
The clinical implementation of secondary prevention implantable cardioverter-defibrillator (ICD) implantation in hemodialysis (HD) patients in Japan remains poorly characterized. We sought to characterize practice patterns and factors associated with secondary prevention ICD implantation in HD patients surviving cardiac arrest due to ventricular arrhythmias.
Methods And Results:
Using the nationwide JROAD-DPC database (2012-2020), we analyzed cardiac arrest survivors with ventricular arrhythmias and no prior ICD. We assessed patient factors associated with ICD implantation and analyzed temporal trends in device selection, institutional and geographical variations in utilization patterns among HD patients. Among 17,653 cardiac arrest survivors, 530 of 1,931 HD patients (27%) received ICDs, significantly lower than 6,870 of 15,722 non-HD patients (44%; P<0.001). Multivariable analysis revealed that HD treatment was an independent negative predictor of ICD implantation (odds ratio 0.42, 95% confidence interval [CI] 0.37-0.47). Subcutaneous-ICD use among HD patients increased significantly from 13% to 32% during 2016-2019 (P<0.001 for trend). Among HD patients, ICD implantation rates were consistent across institutional characteristics and geographical regions.
Conclusions:
This nationwide analysis revealed significantly lower secondary prevention ICD use in HD patients compared to non-HD patients, with consistent implementation patterns across Japan's healthcare system. These findings provide important baseline evidence for developing consensus regarding ICD therapy and underscore the need for future prospective studies to guide optimal ICD selection in this population.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Hemodialysis II: Procedure and Complications
Heart Failure VI: Adjunct Therapies
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiopulmonary Resuscitation III: AED Use
Hemodialysis III: Nursing Management

