Related Experiment Video
Updated: Jan 13, 2026

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
Published on: December 6, 2021
Base Metal Catalysis in Nitrene Transfer Reactions
Hillol Khatua1, Anogh Ghosh1, Subrata Das1
1Department of Chemistry, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008 Maharashtra, India.
Abstract:
Leveraging base metal catalysis to transform small organic molecules by forging X-N bonds (X = C, N, P, S) through nitrene transfer reactions (NTRs) renders a robust and sustainable paradigm shift for preparing valuable amine building blocks. Over the last four decades, 3d metal-catalyzed NTRs have received significant attention in the field of organic synthesis. This review will thoroughly discuss the manipulation of various complexes of base metals, such as Mn, Fe, Co, Ni, and Cu, to control the reaction pathways for X-N bond formation using different nitrene precursors. This review will encompass exemplary, pioneering, and pertinent synthesis in this area and will comprehensively elucidate the mechanistic rationale behind each 3d metals. The reactivity, regioselectivity, chemoselectivity and enantioselectivity of those novel base-metal catalysts are an inevitable part of this discussion. We will also address the inherent limitations and potential opportunities within this specific field of study.
More Related Videos
12:08Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
Published on: June 24, 2022
19:58Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Related Concept Videos
Catalysis
Electrophilic Aromatic Substitution: Nitration of Benzene
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.
Reduction of Alkenes: Catalytic Hydrogenation
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...
Nitriles to Ketones: Grignard Reaction
The mechanism begins with a nucleophilic attack by the Grignard...