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Related Experiment Video

Updated: Jan 13, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
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Recurrent left-sided diverticulitis after surgery: A systematic review and single arm meta-analysis.

Richard Sassun1,2, Francesco Brucchi2, Annaclara Sileo2

  • 1General Surgery Residency Program, University of Milan, Milan, Italy.

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
|January 12, 2026
PubMed
Summary

Elective surgery for left-sided diverticulitis offers durable control, with low long-term recurrence rates of 6.2%. Stoma rates were 17.1% overall, but significantly lower in recent cases, indicating improved outcomes.

Keywords:
diverticulitismeta‐analysisrecurrencestomasurgery

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Epidemiology

Background:

  • Recurrent diverticulitis post-resection is a significant clinical challenge.
  • Potential causes include incomplete resection, synchronous disease, and altered colonic function.
  • Minimally invasive surgical techniques aim to improve outcomes.

Purpose of the Study:

  • To systematically review and meta-analyze long-term recurrence and stoma rates after elective surgery for left-sided diverticulitis.
  • To assess the durability of surgical control in managing this condition.

Main Methods:

  • Systematic review and single-arm meta-analysis following PRISMA guidelines.
  • Searched PubMed, Cochrane, and Scopus databases (2000-2025).
  • Utilized random-effects models for meta-analysis of proportions; assessed study quality using JBI Checklist.

Main Results:

  • Included 24 studies with 7,525 patients; mean follow-up of 53 months.
  • Pooled recurrence rate was 6.2% (95% CI: 4.8-8.0%), consistent across study types and disease severity.
  • Pooled stoma rate was 17.1% (95% CI: 8.4-31.9%), significantly higher in complicated cases and lower in post-2020 studies.

Conclusions:

  • Surgical resection provides durable control of left-sided diverticulitis with low recurrence rates.
  • Stoma rates have significantly decreased in recent years, suggesting procedural improvements.
  • Future research should focus on standardized recurrence definitions, quality of life assessment, and microbiome influences.