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Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...

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Antibacterial Performance of Copper-loaded Mesoporous C3N6.

Jolitta Sheri John Britto1, Thi Kim Anh Tran1, Vibin Perumalsamy1

  • 1Global Innovative Centre For Advanced Nanomaterials (GICAN), School of Engineering, College of Engineering, Science and Environment, The University of Newcastle, Callaghan, Australia.

Small (Weinheim an Der Bergstrasse, Germany)
|January 12, 2026
PubMed
Summary

Copper-loaded carbon nitride nanocomposites (xCu-mC3N6) show enhanced antibacterial activity against Bacillus subtilis and Escherichia coli. This improved efficacy is attributed to increased reactive oxygen species (ROS) production, offering potential for disinfection applications.

Keywords:
anti‐bacterialcarbon nitridemesoporousmetal‐loaded

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemistry

Background:

  • Mesoporous carbon nitride (mC3N6) materials are explored for various applications.
  • Developing effective antibacterial agents is crucial for public health.
  • Nanocomposites offer unique properties for enhanced functionality.

Purpose of the Study:

  • To synthesize copper-loaded mesoporous carbon nitride (xCu-mC3N6) using SBA-15.
  • To evaluate the antibacterial efficacy of xCu-mC3N6 against Gram-positive and Gram-negative bacteria.
  • To investigate the mechanism behind the enhanced antibacterial activity.

Main Methods:

  • Synthesis of xCu-mC3N6 using a hard template method (SBA-15).
  • Characterization using XRD, TEM, nitrogen adsorption-desorption, CHN analysis, and NEXAFS.
  • Antibacterial activity assessment via inhibition zones and colony-counting methods.
  • Intracellular reactive oxygen species (ROS) detection.

Main Results:

  • Successfully synthesized xCu-mC3N6 with a hexagonal porous structure and high surface area.
  • xCu-mC3N6 demonstrated significantly stronger antibacterial effects than mC3N6 against both B. subtilis and E. coli.
  • Increased ROS production was observed in bacteria treated with xCu-mC3N6, indicating ROS-mediated cell death.

Conclusions:

  • Copper loading enhances the antibacterial properties of mesoporous carbon nitride.
  • The enhanced antibacterial activity is linked to ROS generation.
  • These nitrogen-rich nanocomposites show promise for disinfection applications.