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Design, content validation, and reliability assessment of a chemotherapy order template: Expert based content
Vivek Patil1, Madiwalayya S Ganachari1, Manjula Gudhoor1
1Department of Pharmacy Practice, KLE College of Pharmacy, Belagavi, KLE Academy for Higher Education and Research, Belagavi, Karnataka, India.
A validated Chemotherapy Order Template (COT) enhances safe and accurate cancer drug prescribing. This structured tool, based on expert consensus and NCCN guidelines, reduces errors and improves patient care.
Area of Science:
- Oncology
- Pharmacology
- Medical Informatics
Background:
- Cancer is a leading global cause of death, necessitating effective treatments like chemotherapy.
- Chemotherapy administration is complex, posing risks of errors, interactions, and adverse events.
- Standardization is crucial for improving chemotherapy safety and consistency in cancer care.
Purpose of the Study:
- To design, validate, and assess the reliability of a structured Chemotherapy Order Template (COT).
- To ensure safe, accurate, and consistent chemotherapy prescribing in oncology settings.
- To align chemotherapy orders with National Comprehensive Cancer Network (NCCN) guidelines.
Main Methods:
- Development of the COT based on NCCN (2025) guidelines.
- Validation using a 22-item Likert-scale tool and statistical analysis (Pearson's correlation, Cronbach's alpha).
- Multidisciplinary expert review involving 54 healthcare professionals.
Main Results:
- The validation tool exhibited excellent internal consistency (Cronbach's alpha = 0.99).
- All 22 items demonstrated significant positive correlations (p < 0.01), confirming strong construct validity.
- Expert feedback facilitated key improvements to the COT design.
Conclusions:
- The validated COT is a reliable and clinically relevant tool for chemotherapy prescribing.
- The structured template enhances safety, accuracy, and adherence to oncology guidelines.
- Implementation of the COT promotes standardization, reduces medication errors, and supports high-quality cancer care.
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