Association of Handgrip Strength With Functional Capacity and Quality of Life in Adults With Cancer

To evaluate handgrip strength (HGS), functional capacity (FC), and quality of life (QOL) in adults with cancer, and to examine the associations among these variables to explore the potential utility of HGS as an accessible indicator of functional status and well-being in oncology care.

A consecutive sample of 269 adult patients with cancer at Lagos State University Teaching Hospital in Nigeria participated in the study.

A descriptive cross-sectional study measured HGS using a digital hand dynamometer, FC via the FC Index Questionnaire, and QOL through the City of Hope QOL Instrument-Breast Cancer Patient Version adapted for use with all cancer types. Data analysis used descriptive and inferential statistics.

Nearly half (49%) exhibited weak HGS, with only 14% showing strong HGS. A significant number (55%) experienced mild to moderate FC limitations, and the majority (81%) reported moderate to very low QOL. Statistically significant associations were found between HGS and FC, and between HGS and QOL.

Routine assessment of HGS should be incorporated into oncology nursing practice to facilitate early identification of functional decline, guide targeted rehabilitation interventions, and enhance patient-centered care aimed at improving QOL.