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Related Experiment Video

Updated: Jan 14, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
05:11

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

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High-precision path planning for multi-material 3D bioprinting of complex structures.

Wenyu Ning1, Fei Duan1, Lily Raymond2

  • 1State Key Laboratory of High-Performance Precision Manufacturing, School of Mechanical Engineering, Dalian University of Technology, Dalian 116024, People's Republic of China.

Biofabrication
|January 12, 2026
PubMed
Summary

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A multi-parameter performance correlation model to advance the customized design of vascular stents.

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High-Speed Embedded Ink Writing of Anatomic-Size Organ Constructs.

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Multiscale embedded printing of engineered human tissue and organ equivalents.

Proceedings of the National Academy of Sciences of the United States of America·2024

This study introduces a novel printing path strategy for multi-nozzle bioprinting, enhancing efficiency and precision in creating complex tissue models. The method optimizes heterogeneous material deposition for improved geometric fidelity and construct reproducibility.

Area of Science:

  • Bioprinting and Tissue Engineering
  • Materials Science
  • Robotics and Control Systems

Background:

  • Multi-nozzle collaborative bioprinting offers high-precision fabrication of complex tissue models.
  • Challenges include nozzle interference and geometric fidelity issues with heterogeneous materials and asymmetric structures.

Purpose of the Study:

  • To develop and validate a multi-nozzle collaborative and alternating printing path (MN-CAPP) strategy.
  • To optimize the fabrication of complex heterogeneous tissues with improved efficiency and geometric fidelity.

Main Methods:

  • Integration of intra-layer repartitioning and adaptive mode switching for MN-CAPP.
  • Printing of Y-shaped vascular models and size-differentiated scaffolds.
  • Fabrication of a heterogeneous rabbit hepatobiliary model.
Keywords:
bioprintingheterogeneous materialsmulti-nozzlepath planningprinting precision

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Related Experiment Videos

Last Updated: Jan 14, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

8.0K
Planar and Three-Dimensional Printing of Conductive Inks
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Published on: December 9, 2011

37.7K
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
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Main Results:

  • MN-CAPP improved printing efficiency by 32.4% and 33.0% for vascular models compared to single-nozzle printing.
  • Achieved a 33.8% improvement in pore diffusion degree for scaffolds by suppressing edge material stack.
  • Demonstrated ≤ 4% deviation in critical feature dimensions for a complex hepatobiliary model.

Conclusions:

  • MN-CAPP effectively enhances printing efficiency and geometric fidelity for complex heterogeneous tissues.
  • The strategy improves dimensional reproducibility in asymmetric bioprinted structures.
  • Validated effectiveness in fabricating intricate organ models with high precision.