Risk factors for urethrocutaneous fistula following primary hypospadias repair in children: a systematic review and meta-analysis
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Proximal hypospadias and one-stage repair increase urethrocutaneous fistula risk. Shorter stenting and longer defects may also contribute. Staged repair and longer stenting are suggested for high-risk cases.
Area Of Science
- Pediatric Urology
- Surgical Complications
- Hypospadias Repair
Background
- Urethrocutaneous fistula is the most common complication following hypospadias repair.
- Identifying risk factors is crucial for improving surgical outcomes.
Purpose Of The Study
- To conduct a systematic review and meta-analysis to identify modifiable and non-modifiable risk factors for urethrocutaneous fistula formation after primary hypospadias surgery.
Main Methods
- Systematic search of PubMed, Scopus, Embase, Web of Science, and Cochrane databases (Jan 2000 - Nov 2025).
- Inclusion of studies reporting risk factors for fistula after pediatric hypospadias repair with extractable odds ratios or raw data.
- Calculation of pooled odds ratios and mean differences using random-effects models, adhering to PRISMA 2020 guidelines.
Main Results
- Fourteen studies involving 3,794 patients were analyzed.
- Proximal hypospadias (OR 2.03) and one-stage repair (OR 1.67) were significantly associated with increased fistula risk.
- Shorter stenting (<7 days) (OR 3.96) and longer defect length (≥2 cm) (OR 1.57) showed preliminary associations, though based on limited data.
Conclusions
- Proximal meatal location and one-stage repair are robust predictors of urethrocutaneous fistula.
- Shorter stenting and longer urethral defects suggest preliminary associations with higher risk.
- Findings support staged repair for proximal hypospadias and prolonged stenting in selected high-risk patients.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...