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Contemporary Results of Open Surgery for Aortoiliac Occlusive Disease
Georgios S Sfyroeras1, Christos Pitros1, Georgios Plakas1
11st Department of Vascular Surgery, National and Kapodistrian University of Athens Medical School, Attikon Hospital, Athens, Greece.
Insights
Open surgical repair for complex aortoiliac occlusive disease (AIOD) shows low mortality but significant acute kidney injury (AKI) risk, especially with aortobifemoral bypass. Outcomes depend on revascularization technique and disease severity.
Area of Science:
- Vascular Surgery
- Surgical Outcomes Research
Background:
- Open surgical repair remains crucial for complex aortoiliac occlusive disease (AIOD), advanced ischemia, and failed endovascular treatments.
- Contemporary outcomes data for open AIOD repair are limited in current literature.
Purpose of the Study:
- To evaluate perioperative outcomes and complications of open surgical repair for AIOD.
- To assess the influence of disease severity and surgical technique on patient outcomes.
Main Methods:
- Retrospective analysis of 60 patients undergoing open AIOD repair over six years.
- Procedures included aortobifemoral, axillobifemoral, axillofemoral, and iliofemoral bypasses.
- Patients predominantly had TASC D lesions and advanced ischemia (Rutherford categories 4-6).
Main Results:
- Low 30-day mortality (1.7%) and acceptable morbidity.
- Acute kidney injury (AKI) occurred in 20%, higher with aortobifemoral bypass.
- Amputation rates (14%) and hospital stays (21.5 days) increased with disease severity.
- Axillobifemoral/axillofemoral bypasses had fewer complications in high-risk patients.
Conclusions:
- Open surgical management of AIOD at this center demonstrated low perioperative mortality and acceptable morbidity.
- AKI is a significant concern, particularly with aortobifemoral bypass.
- Revascularization technique and Rutherford classification are key determinants of perioperative outcomes in AIOD.
Background:
Despite the enduring importance of open surgical repair for complex aortoiliac occlusive disease (AIOD), advanced ischemia, or cases with failed endovascular therapy, there remains a notable gap in the current literature regarding contemporary outcomes of open surgery for AIOD. This study retrospectively analyzed 6 years of open revascularization procedures at our institution to evaluate perioperative outcomes, complications, and the influence of disease severity and procedure type.
Method:
A total of 60 patients (mean age 64.8 years; predominantly male) underwent open AIOD repair, with most classified as TransAtlantic Inter-Society Consensus D lesions. Most of them (72%) presented with advanced ischemia classified as Rutherford categories 4, 5, or 6. The majority received aortobifemoral bypass (n = 39), while others underwent axillobifemoral (n = 8), axillofemoral (n = 6), or iliofemoral (n = 8) bypass procedures.
Results:
Acute kidney injury (AKI) occurred in 20% of patients, primarily following aortobifemoral bypass (28%). Postoperative AKI was associated with significantly lower preoperative renal function. Dialysis and major cardiovascular events each affected 3.3% of the cohort. Fourteen percent required amputation, predominantly among those with higher Rutherford classifications (up to 67% in stage 6). The mean hospital length of stay was 21.5 days;intensive care unit admission was necessary in 44% of cases (mean duration 1.8 days). Thirty-day mortality was 1.7%. Aortobifemoral bypasses were more frequently performed in younger, patients and were associated with increased complication rates. In contrast, axillobifemoral and axillofemoral bypasses, performed in older and high-risk populations, were linked to fewer complications. Iliofemoral bypasses were associated with the longest hospital stays but minimal complications. Statistical analysis demonstrated significant differences among the groups (P < 0.05).
Conclusion:
At our center, open surgical management of AIOD yielded low perioperative mortality and acceptable morbidity rates. AKI was frequent, particularly in patients undergoing aortobifemoral bypass and those with less advanced ischemia. Amputation rates and hospital stays increased with greater disease severity. Both the revascularization technique and Rutherford classification significantly impacted perioperative outcomes.
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