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Area of Science:

  • Biomedical Imaging
  • Terahertz Spectroscopy
  • Non-invasive Diagnostics

Background:

  • Existing terahertz (THz) systems lack speed and adaptability for in situ applications.
  • There is a need for real-time, non-invasive imaging in diagnostics and material analysis.

Purpose of the Study:

  • To present a novel, fully fibre-coupled THz imaging system.
  • To overcome limitations of current THz systems for in situ biomedical use.

Main Methods:

  • Developed a fibre-coupled THz attenuated total internal reflection single-pixel imaging system.
  • Utilized an unpassivated silicon wafer as a THz spatial light modulator.
  • Achieved reflection geometry with fibre-coupled light.

Main Results:

  • Demonstrated a compact, flexible, and robust platform for non-destructive spectroscopy and in vivo imaging.
  • Enabled video-rate imaging with 360 μm spatial resolution.
  • Achieved an imaging throughput over 30,000 pixels/second (64x64 images), exceeding the state of the art by over five-fold.

Conclusions:

  • The fibre-coupled THz system offers a substantial improvement in real-time imaging capabilities.
  • The system is suitable for seamless integration in in situ biomedical applications, including direct patient measurements.
  • High-speed modulation and fibre coupling enhance THz imaging performance and versatility.