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A hybrid model for improved nail disease classification using vision transformers and stable diffusion.

Rahul Nijhawan1, Ananya Gupta1, Manoj Diwakar2,3

  • 1Thapar Institute of Engineering and Technology, Patiala, Punjab, India.

Scientific Reports
|January 12, 2026
PubMed
Summary
This summary is machine-generated.

Synthetic data generated by stable diffusion models improves machine learning accuracy for diagnosing nail diseases. This approach enhances diagnostic tools, leading to more accurate and timely treatments for conditions like fungal infections and psoriasis.

Keywords:
Data augmentationNail diseaseNail disease datasetStable diffusionText-to-imageTransfer learning

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Area of Science:

  • Dermatology
  • Artificial Intelligence
  • Medical Imaging

Background:

  • Nail diseases are common and often diagnosed through visual inspection, which can lead to inaccuracies and treatment delays.
  • Accurate and timely diagnosis is crucial for effective management of nail conditions such as fungal infections, paronychia, and psoriasis.

Purpose of the Study:

  • To investigate the use of synthetic nail disease data generated via stable diffusion models to improve machine learning diagnostic accuracy.
  • To enhance data transformation techniques using few-shot learning within a text-to-image stable diffusion model for generating diverse synthetic data.

Main Methods:

  • Generation of synthetic nail disease data using stable diffusion models with few-shot learning.
  • Application of synthetic data to augment a custom real-world nail disease dataset.
  • Evaluation of pre-trained Convolutional Neural Network (CNN) MobileNetV2 and Vision Transformer models with the augmented dataset.

Main Results:

  • Synthetic data improved the robustness of both MobileNetV2 and Vision Transformer models.
  • MobileNetV2 achieved an accuracy increase of 3.26%.
  • Vision Transformer achieved an accuracy increase of 3.02%.

Conclusions:

  • Synthetic data generated by stable diffusion models is effective in enhancing the performance of machine learning models for nail disease classification.
  • This approach offers a promising method to improve the accuracy and reliability of automated nail disease diagnosis, potentially reducing diagnostic errors and treatment delays.