Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cost-effectiveness of the gluteal turnover flap for perineal wound closure after abdominoperineal resection: randomized clinical trial.

BJS open·2026
Same author

Impact of stoma revision surgery on quality of life: the STICK-II retrospective cohort study.

Techniques in coloproctology·2026
Same author

A national, multicentre, randomised, controlled, parallel-arms, phase III clinical trial of neoadjuvant FOLFOXIRI and chemoradiotherapy versus neoadjuvant CAPOX/FOLFOX and chemoradiotherapy in patients with high-risk locally advanced rectal cancer: study protocol of the MEND-IT II trial.

BMC cancer·2026
Same author

Defining disease recurrence after curative treatment of esophageal cancer: a literature review.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

The challenge of informed consent: Propensity score weighting to prevent selection bias.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Prediction of pneumonia following neoadjuvant chemoradiotherapy in patients with oesophageal cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Related Experiment Video

Updated: Jan 14, 2026

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy
04:38

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

589

Radial fan-based CO2 insufflation during laparoscopic surgery: a first-in-human study.

A I de Jong1, E Ghilotti2,3, F Sterke2,4

  • 1Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands. a.i.dejong@erasmusmc.nl.

Surgical Endoscopy
|January 12, 2026
PubMed
Summary
This summary is machine-generated.

A new radial fan-based insufflator (RFBI) safely and effectively maintained stable carbon dioxide (CO2) insufflation pressures during laparoscopic surgery. This novel technology proved feasible in a first-in-human study, compensating for ventilation and surgical disruptions.

Keywords:
InnovationInsufflationLaparoscopic surgeryPneumoperitoneumPressure stabilityRadial fan

More Related Videos

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
08:50

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy

Published on: June 25, 2013

13.6K
CO2-Lasertonsillotomy Under Local Anesthesia in Adults
05:07

CO2-Lasertonsillotomy Under Local Anesthesia in Adults

Published on: November 6, 2019

26.0K

Related Experiment Videos

Last Updated: Jan 14, 2026

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy
04:38

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

589
Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
08:50

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy

Published on: June 25, 2013

13.6K
CO2-Lasertonsillotomy Under Local Anesthesia in Adults
05:07

CO2-Lasertonsillotomy Under Local Anesthesia in Adults

Published on: November 6, 2019

26.0K

Area of Science:

  • Minimally Invasive Surgery
  • Surgical Technology Innovation
  • Laparoscopic Procedure Optimization

Background:

  • Mechanical ventilation significantly impacts intra-abdominal pressure during laparoscopic insufflation with carbon dioxide (CO2).
  • Pressure fluctuations can destabilize the surgical workspace and increase risks associated with high insufflation pressures.
  • A novel radial fan-based insufflator (RFBI) was developed to provide stable insufflation pressures.

Purpose of the Study:

  • To evaluate the safety and feasibility of a novel radial fan-based insufflator (RFBI) in adult laparoscopic surgery.
  • To assess the RFBI's ability to maintain stable intra-abdominal pressure during procedures.
  • To document adverse events and pressure stability during insufflation.

Main Methods:

  • A first-in-human study included adult patients undergoing elective intraperitoneal laparoscopic procedures.
  • All procedures utilized the RFBI and an 11 mm study trocar.
  • Safety (absence of serious adverse device effects) and feasibility (no switch to conventional insufflator) were primary outcomes; pressure stability was a secondary outcome.

Main Results:

  • Twelve patients underwent procedures with a total of 35.9 hours of RFBI use across seven laparoscopic surgery types.
  • No serious adverse device effects occurred; one adverse device effect (trocar insertion-related air leak) caused temporary workspace disruption but no harm.
  • Procedures were completed without switching to conventional insufflators, and the RFBI maintained stable pressures (10 mmHg and 14 mmHg) and rapidly re-established target pressure after disruptions.

Conclusions:

  • The radial fan-based insufflator (RFBI) technology is safe and feasible for adult laparoscopic procedures.
  • RFBI effectively maintains stable insufflation pressures, compensating for ventilation and surgical events.
  • Further research is warranted to explore the clinical benefits of this innovative insufflation technology.