Related Experiment Video
Updated: Jul 13, 2026
08:50
Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
Published on: June 25, 2013
13.6K
Radial fan-based CO2 insufflation during laparoscopic surgery: a first-in-human study
A I de Jong1, E Ghilotti2,3, F Sterke2,4
1Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands. a.i.dejong@erasmusmc.nl.
Surgical Endoscopy
|January 12, 2026
Summary
A new radial fan-based insufflator (RFBI) safely and effectively maintained stable carbon dioxide (CO2) insufflation pressures during laparoscopic surgery. This novel technology proved feasible in a first-in-human study, compensating for ventilation and surgical disruptions.
Area of Science:
- Minimally Invasive Surgery
- Surgical Technology Innovation
- Laparoscopic Procedure Optimization
Background:
- Mechanical ventilation significantly impacts intra-abdominal pressure during laparoscopic insufflation with carbon dioxide (CO2).
- Pressure fluctuations can destabilize the surgical workspace and increase risks associated with high insufflation pressures.
- A novel radial fan-based insufflator (RFBI) was developed to provide stable insufflation pressures.
Purpose of the Study:
- To evaluate the safety and feasibility of a novel radial fan-based insufflator (RFBI) in adult laparoscopic surgery.
- To assess the RFBI's ability to maintain stable intra-abdominal pressure during procedures.
- To document adverse events and pressure stability during insufflation.
Main Methods:
- A first-in-human study included adult patients undergoing elective intraperitoneal laparoscopic procedures.
- All procedures utilized the RFBI and an 11 mm study trocar.
- Safety (absence of serious adverse device effects) and feasibility (no switch to conventional insufflator) were primary outcomes; pressure stability was a secondary outcome.
Main Results:
- Twelve patients underwent procedures with a total of 35.9 hours of RFBI use across seven laparoscopic surgery types.
- No serious adverse device effects occurred; one adverse device effect (trocar insertion-related air leak) caused temporary workspace disruption but no harm.
- Procedures were completed without switching to conventional insufflators, and the RFBI maintained stable pressures (10 mmHg and 14 mmHg) and rapidly re-established target pressure after disruptions.
Conclusions:
- The radial fan-based insufflator (RFBI) technology is safe and feasible for adult laparoscopic procedures.
- RFBI effectively maintains stable insufflation pressures, compensating for ventilation and surgical events.
- Further research is warranted to explore the clinical benefits of this innovative insufflation technology.
Related Concept Videos
01:26Endoscopic Studies II: Thoracocentesis
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
01:23Mechanical Ventilation II: Invasive Ventilation
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
01:23Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Noninvasive Positive-Pressure Ventilation (NIPPV)
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...