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Related Experiment Videos

Listeria monocytogenes meningitis: case report.

J Reddy, J A Malloch, R A Leng

    The New Zealand Medical Journal
    |June 22, 1977
    PubMed
    Summary

    This case study details Listeria monocytogenes septicemia and meningitis in a patient with chronic liver disease, diabetes mellitus, and liver malignancy. The infection showed poor response to ampicillin treatment.

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    Area of Science:

    • Infectious Diseases
    • Neurology
    • Hepatology

    Background:

    • Listeria monocytogenes is a significant pathogen causing severe infections, particularly in immunocompromised individuals.
    • Septicemia and meningitis are serious complications of Listeria monocytogenes infection.
    • Chronic liver disease, diabetes mellitus, and liver malignancy are known predisposing factors for invasive infections.

    Observation:

    • A case of Listeria monocytogenes septicemia with concurrent meningitis is presented.
    • The patient had multiple comorbidities including chronic liver disease, diabetes mellitus, and liver malignancy.
    • Clinical presentation indicated a severe systemic and central nervous system infection.

    Findings:

    • The causative agent was identified as Listeria monocytogenes.
    • The infection presented as both septicemia and meningitis.
    • Treatment with ampicillin demonstrated a poor response, suggesting potential antibiotic resistance or disease severity.

    Implications:

    • This case highlights the importance of considering Listeria monocytogenes in patients with predisposing conditions presenting with sepsis and meningitis.
    • The poor response to ampicillin underscores the need for vigilant monitoring and potential alternative therapeutic strategies in complex cases.
    • Further research into optimal treatment regimens for Listeria monocytogenes infections in immunocompromised hosts is warranted.

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