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Listeria monocytogenes meningitis: case report
The New Zealand Medical Journal
|June 22, 1977
Abstract:
A case of Listeria monocytogenes septicaemia with meningitis is described. Predisposing factors in this case included chronic liver disease, diabetes mellitus and liver malignancy. The infection responded poorly to ampicillin.
Insights
This case study details Listeria monocytogenes septicemia and meningitis in a patient with chronic liver disease, diabetes mellitus, and liver malignancy. The infection showed poor response to ampicillin treatment.
Area of Science:
- Infectious Diseases
- Neurology
- Hepatology
Background:
- Listeria monocytogenes is a significant pathogen causing severe infections, particularly in immunocompromised individuals.
- Septicemia and meningitis are serious complications of Listeria monocytogenes infection.
- Chronic liver disease, diabetes mellitus, and liver malignancy are known predisposing factors for invasive infections.
Observation:
- A case of Listeria monocytogenes septicemia with concurrent meningitis is presented.
- The patient had multiple comorbidities including chronic liver disease, diabetes mellitus, and liver malignancy.
- Clinical presentation indicated a severe systemic and central nervous system infection.
Findings:
- The causative agent was identified as Listeria monocytogenes.
- The infection presented as both septicemia and meningitis.
- Treatment with ampicillin demonstrated a poor response, suggesting potential antibiotic resistance or disease severity.
Implications:
- This case highlights the importance of considering Listeria monocytogenes in patients with predisposing conditions presenting with sepsis and meningitis.
- The poor response to ampicillin underscores the need for vigilant monitoring and potential alternative therapeutic strategies in complex cases.
- Further research into optimal treatment regimens for Listeria monocytogenes infections in immunocompromised hosts is warranted.