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Updated: Jan 14, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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Infection-Independent Effect of the COVID-19 Pandemic on Diabetes and Cardiovascular Disease Mortality: An Illinois

Jon E Niederhauser1,2, Patrick C Harper2,3,4, Philip Pittman2

  • 1Department of Public Health, University of Illinois Springfield, Springfield, IL, USA.

Public Health Reports (Washington, D.C. : 1974)
|January 13, 2026
PubMed

Insights

The COVID-19 pandemic increased diabetes and cardiovascular disease (CVD) mortality, even without COVID-19 infection. These findings highlight the pandemic's indirect impact on chronic disease management and mortality rates.

Area of Science:

  • Public Health
  • Epidemiology
  • Chronic Disease Management

Background:

  • The COVID-19 pandemic disrupted healthcare, affecting chronic disease detection and management.
  • Infection control measures and infrastructure challenges impacted lifestyle choices, potentially worsening chronic conditions.

Purpose of the Study:

  • To analyze diabetes and cardiovascular disease (CVD) mortality rates independent of COVID-19 infection.
  • To assess the pandemic's infection-independent effect on chronic disease mortality in Illinois.

Main Methods:

  • Utilized Illinois Vital Records System death records from 2019 and COVID-19 Year 1 (March 2020-March 2021).
  • Included deaths from diabetes or CVD without COVID-19 infection.
  • Calculated age-adjusted mortality rates, examining variations by demographics and CVD subtypes.

Main Results:

  • All-cause mortality (excluding COVID-19) increased by 3.6% during the study period.
  • Diabetes mortality saw a significant 19.9% rise.
  • Cardiovascular disease (CVD) mortality increased by 3.9%, mirroring the all-cause trend. Increases were more pronounced in specific demographic groups.

Conclusions:

  • The COVID-19 pandemic exerted an infection-independent influence on chronic disease mortality.
  • Findings underscore the need for public health policies to safeguard chronic disease care during health crises.
Abstract

Keywords:
COVID-19Illinoiscause of deathchronic diseaseracial and ethnic minority groups

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