Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Electrospun Ti-Zr Oxide Heterostructures Enable Strongly Anchored Ultralow-Ir Anodes for Durable Acidic Oxygen Evolution.

Journal of the American Chemical Society·2026

Same author

A dual membrane-adsorption evaporator for solar-powered lithium extraction from complex brines.

Science advances·2026

Same author

Non-equilibrium reducing flame aerosol process to create supported high-entropy alloy nanoparticles.

Nature communications·2026

Same author

Transformation of CeO<sub>2</sub> Nanoparticles into Atomically Dispersed Ce Cations Leads to Enhanced Reactivity for Automotive Emissions Control.

Journal of the American Chemical Society·2026

Same author

Multifunctional ligand engineering for pure-blue halide perovskite nanocrystal LEDs.

Light, science & applications·2026

Same author

Designing a Dry Cathode via Hydrogen-Bond Network Regulation at Phosphide Heterostructure/Electrolyte Interfaces for Alkaline Water Electrolysis.

Journal of the American Chemical Society·2026

Search research articles

Related Experiment Video

Updated: Jan 14, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Published on: October 27, 2018

Non-Equilibrium Synthesis Methods to Create Metastable and High-Entropy Nanomaterials.

Shuo Liu^1,2, Chaochao Dun¹, Jeffrey J Urban¹

¹The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California, USA.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|January 13, 2026

Summary

Non-equilibrium synthesis enables mixing immiscible elements into advanced materials. These metastable, high-entropy nanostructures overcome thermodynamic limits for novel applications in catalysis and energy.

Keywords:

high‐entropy materials metastable nanomaterials non‐equilibrium synthesis

More Related Videos

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Published on: April 2, 2015

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Published on: November 27, 2015

Related Experiment Videos

Last Updated: Jan 14, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Published on: October 27, 2018

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Published on: April 2, 2015

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Published on: November 27, 2015

Area of Science:

Materials Science
Inorganic Chemistry
Nanotechnology

Background:

Stabilizing multiple elements in a single phase creates advanced materials with unique properties.
Hume-Rothery rules limit solid-state miscibility under equilibrium conditions, restricting material composition.
This limitation narrows the scope for discovering new inorganic materials.

Purpose of the Study:

To review how non-equilibrium synthesis methods overcome thermodynamic barriers.
To highlight the integration of immiscible elements into metastable and high-entropy nanostructures.
To discuss the potential of these materials in catalysis, energy storage, thermoelectrics, and sensing.

Main Methods:

Ultrafast heating and quenching techniques are employed.
Non-equilibrium synthesis enables kinetic trapping and stabilization via high configurational entropy.
These methods generate unconventional compositions and nanostructures.

Main Results:

Metastable and high-entropy nanostructures are formed from immiscible elements.
Enhanced phase stability is achieved through kinetic trapping and entropy stabilization.
Unique structural and functional properties arise from these complex compositions.

Conclusions:

Non-equilibrium synthesis dramatically expands the accessible material design space.
These methods offer rich datasets for AI-guided materials discovery.
The high-throughput and scalable nature of these approaches accelerate materials development and industrial production.