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Published on: May 23, 2020
A Case of Mandibular Osteomyelitis Occurring in a Patient With Parry-Romberg Syndrome
Riyu Koguchi-Yoshida1, Michita Tayama2, Hiroshi Kaneko3
1Department of Pharmacology/Department of Oral Diagnosis and Medicine, Hokkaido University, Faculty and Graduate School of Dental Medicine, Sapporo, JPN.
Abstract:
Progressive hemifacial atrophy, also known as Parry-Romberg syndrome (PRS), is an idiopathic disorder characterized by progressive unilateral facial depression caused by atrophy of the skin and subcutaneous tissue. We present a case of mandibular osteomyelitis occurring in a patient with this condition, together with a review of the literature. The clinical findings in this case suggest that autoimmune disease and trauma are involved in contributing factors to disease progression. Possible involvement of neurovascular and neuroskeletal dysregulations in the pathogenesis of PRS is also discussed.
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