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Updated: Jun 13, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
[Pilocytic astrocytomas with aggressive clinical course: a single-center experience]
Yu M Poluektov1, D Yu Usachev1, N A Konovalov1
1Burdenko Neurosurgical Center, Moscow, Russia.
Aggressive pilocytic astrocytomas (PA) show a poorer prognosis, with a 45% 5-year survival rate compared to conventional PAs. Histological signs like anaplasia and high Ki-67 index can indicate aggressive tumors.
Area of Science:
- Neuro-oncology
- Pathology
- Clinical Medicine
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