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Response to: 'Gentamicin ointment effect on hard-to-heal wounds: a case series'

Igor Melnychuk1,2,3

  • 1Clinical Associate Professor, Edward Via College of Osteopathic Medicine Carolinas, Spartanburg, South Carolina, US.

Journal of Wound Care
|January 13, 2026
PubMed
Abstract

No abstract available in PubMed .

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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