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Related Experiment Video

Updated: Jan 15, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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GHAttack: Generative Adversarial Attacks on Heterogeneous Graph Neural Networks.

Shaoxin Li, Xiaofeng Liao, Huanzhang Zhu

    IEEE Transactions on Neural Networks and Learning Systems
    |January 13, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces Generative Heterogeneous Attack (GHAttack), a new method for efficiently attacking Heterogeneous Graph Neural Networks (HGNNs). GHAttack generates perturbations quickly, making adversarial attacks on HGNNs more practical.

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    Last Updated: Jan 15, 2026

    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
    05:47

    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

    Published on: June 13, 2025

    1.3K

    Area of Science:

    • Artificial Intelligence
    • Machine Learning
    • Graph Neural Networks

    Background:

    • Heterogeneous Graph Neural Networks (HGNNs) are increasingly used but vulnerable to adversarial attacks.
    • Current HGNN attack methods are computationally expensive, limiting their use during inference.

    Purpose of the Study:

    • To develop an efficient and effective adversarial attack method for HGNNs.
    • To address the computational inefficiency of existing HGNN attack strategies.

    Main Methods:

    • Introduced Generative Heterogeneous Attack (GHAttack), a novel generative attack approach.
    • Developed a perturbation generator trained via an optimization problem, utilizing an HGNN backbone and relation-aware output layer.
    • Enabled perturbations to modify edges within heterogeneous graph relations for enhanced attack effectiveness.

    Main Results:

    • GHAttack demonstrated high efficiency and excellent effectiveness in experiments.
    • Validated across ten representative HGNNs and six datasets.
    • The generative approach allows for rapid perturbation generation through a simple forward pass.

    Conclusions:

    • GHAttack offers a computationally efficient solution for adversarial attacks on HGNNs.
    • The method is effective in degrading HGNN performance by perturbing graph structures.
    • This work advances the field of adversarial robustness for graph-based machine learning models.