Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

143
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
143

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of progressive resistance training on lean soft tissue mass in head and neck cancer patients during concomitant chemoradiotherapy: the DAHANCA 31 randomized controlled trial.

Acta oncologica (Stockholm, Sweden)·2026
Same author

Single nucleus RNA sequencing reveals testosterone replacement therapy-associated multicellular remodelling of skeletal muscle in hypogonadal men with Klinefelter Syndrome.

The Journal of clinical endocrinology and metabolism·2026
Same author

Defining the vascular niche of human adipose tissue across metabolic states.

Nature metabolism·2026
Same author

Association of the Tilburg Frailty Indicator with mortality, readmission, and healthcare contacts in adult patients with multimorbidity.

Journal of multimorbidity and comorbidity·2026
Same author

Genetic diagnosis of CYP21A2-related CAH: adaptive sampling long-read sequencing is an accurate and scalable solution.

European journal of human genetics : EJHG·2026
Same author

Ketone supplementation dose-dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study.

Diabetologia·2025

Related Experiment Video

Updated: Jan 15, 2026

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
05:42

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Published on: January 7, 2019

32.5K

Continuous Ketone Monitoring: Data From a Randomized Controlled Trial.

Simon K Kjær1,2, Lukas Ochsner Reynaud Ridder2,3, Mads Svart2,4

  • 1Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.

JMIR Diabetes
|January 13, 2026
PubMed
Summary

Continuous ketone monitoring devices may show declining readings over time due to sensor drift, even when measuring beta-hydroxybutyrate (BHB) during exogenous ketosis. This impacts the reliability of tracking ketone levels over extended periods.

Keywords:
beta-hydroxybutyratecontinuous ketone monitoringexogenous ketosisketone esterketone sensor technology

More Related Videos

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

1.9K
Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
06:13

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

1.6K

Related Experiment Videos

Last Updated: Jan 15, 2026

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
05:42

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Published on: January 7, 2019

32.5K
Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

1.9K
Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
06:13

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

1.6K

Area of Science:

  • Metabolic Health
  • Biotechnology
  • Nutritional Science

Background:

  • Exogenous ketosis is often studied for its potential health benefits.
  • Accurate monitoring of ketone bodies, such as beta-hydroxybutyrate (BHB), is crucial for research.
  • Continuous monitoring devices offer potential for real-time insights into metabolic states.

Purpose of the Study:

  • To evaluate the performance of a commercial continuous ketone monitoring device.
  • To assess beta-hydroxybutyrate (BHB) dynamics during exogenous ketosis over 14 days.
  • To identify potential limitations in continuous ketone monitoring technology.

Main Methods:

  • Utilized a commercially available continuous ketone monitoring device.
  • Measured beta-hydroxybutyrate (BHB) levels in participants undergoing exogenous ketosis.
  • Included both ketone ester and placebo groups for comparison.
  • Monitored BHB concentrations over a 14-day period.

Main Results:

  • The continuous ketone monitoring device captured BHB dynamics.
  • A consistent, gradual decline in daily BHB concentrations was observed.
  • This decline occurred in both the ketone ester and placebo groups.
  • The observed decline is likely attributable to sensor drift.

Conclusions:

  • Commercial continuous ketone monitoring devices may be subject to sensor drift.
  • This drift can affect the accuracy of long-term BHB measurements.
  • Further validation and calibration are necessary for reliable continuous ketone monitoring.