Related Experiment Video
Updated: Jan 15, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
A discrete nonlinear model for HPV immune suppression and evasion
Francisco J Solis1, Luz M Gonzalez2
1CIMAT, Applied Mathematics, Guanajuato, 36000, México.
Abstract:
In this paper we present a nonlinear discrete model in order to describe defective interactions of immune system cells with Human Papillomavirus (HPV) infected cells. Statistics show than only a percentage of the HPV infected population will develop malignancy diseases. Our goal is to develop a prototypical mathematical model that is analitically tratable with a statistical complexity to reproduce qualitative and quantitative information of the consequences of HPV-evasion of host defenses and suppression of an efficient immune response. Numerical results obtained from the model confirm the intrinsic relationships of its nonlinear terms representing the earlier evolution of mature infected cells with a successful virus invasion.
Related Concept Videos
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Mechanisms of Retrovirus-induced Cancers
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
Viruses with RNA Genomes

