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Isolation and Functional Analysis of Mitochondria from Cultured Cells and Mouse Tissue
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Corrigendum to "Effect of alternative oxidase (AOX) expression on mouse cerebral mitochondria bioenergetics" [Redox

Belem Yoval-Sánchez1, Ivan Guerrero1, Fariha Ansari1

  • 1Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA.

Redox Biology
|January 13, 2026
PubMed
Abstract

No abstract available in PubMed .

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Electron Transport Chain: Complex I and II01:46

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The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...

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