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Related Concept Videos

Classification of Bones01:18

Classification of Bones

The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...

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Towards Automated Craniosynostosis Diagnosis Using EfficientNet-Based Artificial Intelligence Models: A Two-Class and

Varekan Keishing1,2, Edward S Ahn3, Zenith Khashim4

  • 1Mayo Clinic Artificial Intelligence Lab, Department of Radiology, Mayo Clinic, 200, 1st Street, S.W., Rochester, MN, 55905, USA.

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Artificial intelligence (AI) models can now detect craniosynostosis, a birth defect, using standard 2D head photos. This non-invasive AI approach offers accurate early diagnosis, improving surgical outcomes and accessibility for infants.

Keywords:
Artificial intelligenceCraniosynostosisEfficientNetImage classificationMachine learning

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Pediatric Surgery

Background:

  • Craniosynostosis, premature fusion of infant skull bones, can cause disfigurement and impede brain growth.
  • Current diagnosis often relies on computed tomography (CT), involving radiation exposure and potential delays.
  • Early detection is crucial for less invasive surgical interventions and improved patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of state-of-the-art AI architectures for detecting craniosynostosis using standard 2D clinical photographs.
  • To compare the performance of EfficientNet-B7, ResNet-50, and ResNet-152 models in binary and multi-class craniosynostosis classification.
  • To establish a non-invasive, radiation-free diagnostic tool for craniosynostosis.

Main Methods:

  • Trained and tested EfficientNet-B7, ResNet-50, and ResNet-152 models on 688 clinical 2D photographs.
  • Utilized five random seeds for robust evaluation of binary and multi-class classification tasks.
  • Focused on standard photographs, avoiding specialized imaging like X-ray, CT, or photogrammetry.

Main Results:

  • All models achieved high accuracy in binary classification, with EfficientNet-B7 reaching 99.7% accuracy and perfect sensitivity.
  • EfficientNet-B7 demonstrated superior performance in multi-class classification (96.6% accuracy), outperforming ResNet-50.
  • AI models successfully classified craniosynostosis subtypes using only standard 2D images.

Conclusions:

  • AI models trained on 2D photographs provide accurate, cost-effective, and non-invasive craniosynostosis detection and classification.
  • This approach supports timely intervention, potentially expanding access to care in diverse healthcare settings.
  • This study pioneers high-accuracy craniosynostosis classification using readily available clinical photographs.