Related Experiment Video
Updated: Jan 15, 2026

07:42
Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
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Posterior Reversible Encephalopathy Syndrome as an Unusual Complication of Routine Chemotherapy: A Case Report
Ahmed Osman1, Maximilian Bonnici1, Samruddhi Jain1
1Radiology, St. Vincent Hospital, Worcester, USA.
Cureus
|January 14, 2026
Summary
Posterior reversible encephalopathy syndrome (PRES) can be induced by chemotherapy, specifically gemcitabine. Early recognition and management of PRES are crucial to prevent permanent neurological damage.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disorder.
- Chemotherapy, particularly gemcitabine, is increasingly implicated in PRES induction.
- The exact mechanism of gemcitabine-induced PRES, likely involving endothelial dysfunction and vasogenic edema, remains poorly understood.
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