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Updated: Jan 15, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties

Bruna F Godoi1,2, Jéssica D Bueno1,2, Wemenes J L Silva1,3,4

  • 1Center for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.

ACS Medicinal Chemistry Letters
|January 14, 2026
PubMed

Keywords:
SARS-CoV-2SBDDhost-directed therapyhuman dihydroorotate dehydrogenasequinazol­inones

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