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Updated: Jan 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Relationship Between Circulatory Stasis in the Left Atrial Appendage Detected by Cardiac Computed Tomography
Shu Yang1,2, Jun Wang3, Ning Chen2
1Division of Cardiology The Affiliated Taizhou People's Hospital of Nanjing Medical University Taizhou Jiangsu China.
Insights
Circulatory stasis in the left atrial appendage (LAA) is a significant predictor of atrial fibrillation (AF) recurrence after catheter ablation. Identifying LAA stasis can improve risk prediction for AF recurrence in patients undergoing ablation.
Area of Science:
- Cardiology
- Medical Imaging
- Electrophysiology
Background:
- Atrial fibrillation (AF) is a common arrhythmia.
- Catheter ablation is a standard treatment for AF.
- Left atrial appendage (LAA) stasis is a potential risk factor for thromboembolic events in AF patients.
Purpose of the Study:
- To investigate the association between left atrial appendage (LAA) circulatory stasis and atrial fibrillation (AF) recurrence after catheter ablation.
- To determine if LAA stasis improves the prediction of AF recurrence.
Main Methods:
- Prospective observational study of 548 patients with nonvalvular AF undergoing initial catheter ablation.
- Cardiac computed tomography angiography used to assess LAA circulatory stasis.
- One-year follow-up to monitor for AF recurrence.
Main Results:
- 131 patients (23.9%) had LAA circulatory stasis.
- AF recurrence occurred in 39.1% of patients with LAA stasis vs. 19.4% without.
- LAA stasis significantly predicted AF recurrence (adjusted HR, 2.41).
- LAA stasis improved predictive accuracy of scoring systems for AF recurrence.
Conclusions:
- Circulatory stasis in the LAA is a significant predictor of AF recurrence post-ablation.
- Assessing LAA stasis can enhance risk stratification for AF recurrence.
Background:
To investigate the relationship between circulatory stasis in the left atrial appendage (LAA), as detected by cardiac computed tomography angiography, and atrial fibrillation (AF) recurrence after the initial catheter ablation.
Methods:
In this single-center prospective observational study, consecutive patients with nonvalvular AF scheduled for the initial catheter ablation were enrolled from August 2018 to June 2022. The primary end point was AF recurrence (any documented atrial tachyarrhythmia lasting for ≥30 seconds after a 3-month blanking period) during 1 year after catheter ablation.
Results:
Among the enrolled 548 patients (mean age 65.3±8.8 years and 64.2% men), 131 (23.9%) were with LAA circulatory stasis. Totally, 525 patients completed the 1-year follow-up. AF recurrence was observed in 39.1% (50/128) of patients with circulatory stasis and 19.4% (77/397) of patients without circulatory stasis. The presence of LAA circulatory stasis was significantly associated with AF recurrence (adjusted hazard ratio [HR], 2.41 [95% CI, 1.57-3.72]). The incorporation of circulatory stasis in the LAA significantly improved the predictive accuracy of conventional scoring systems for AF recurrence, with the areas under the curve increasing from 0.524 to 0.616 (P=0.037) for the APPLE score, from 0.516 to 0.617 (P=0.035) for the CAAP-AF score, and from 0.532 to 0.619 (P=0.001) for the CHA2DS2-VASc score.
Conclusions:
In patients with nonvalvular AF, circulatory stasis in the LAA could serve as a predictor for AF recurrence following the initial ablation procedure.
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