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Updated: Jan 17, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Palladium-Catalyzed Decarboxylative C─H Alkenylation of Proaromatic Acids With Allyl Alcohols and N-Allyl
Yin-Chia Lu1, Veerabhushanam Kadiyala1, Prahallad Meher2
1Department of Applied Chemistry, National University of Kaohsiung, Kaohsiung, Taiwan.
Abstract:
We develop an efficient palladium-catalyzed decarboxylative C─H alkenylation of cyclohexa-2,5-dienyl carboxylic acids with allylic alcohols and N-allyl sulfonamides, enabling regioselective access to diverse vinylarenes. The transformation proceeds under mild, operationally simple conditions and tolerates a broad range of alkyl, aryl, and heteroaryl substituents. Mechanistic studies reveal that the reaction is going via carboxylate-directed C─H activation and olefin insertion step. The method is scalable and offers a practical route to vinylarene scaffold-containing biologically relevant moieties.
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