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    This study introduces a novel real-time method for designing gradient waveforms in magnetic resonance imaging, significantly reducing computation time and slew-rate error for arbitrary k-space trajectories.

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    Area of Science:

    • Magnetic Resonance Imaging (MRI)
    • Medical Physics
    • Signal Processing

    Background:

    • Designing gradient waveforms for arbitrary k-space trajectories is crucial for advanced MRI techniques.
    • Existing methods often face limitations in real-time applicability and hardware compliance.

    Purpose of the Study:

    • To develop a real-time, hardware-compliant method for designing time-optimal gradient waveforms.
    • To accommodate arbitrary k-space trajectories in MRI gradient waveform design.

    Main Methods:

    • A recursive approach solves gradient waveforms under slew-rate and trajectory constraints, forming a quadratic equation.
    • Gradient constraints are enforced using L2-norm thresholding and escape velocity.
    • Discrete-Time Forward and Backward Sweep strategy refines slew-rate constraints.
    • Trajectory and gradient reparameterization enhance generality and sampling accuracy.

    Main Results:

    • Achieved over 89% reduction in computation time and over 98% reduction in slew-rate error.
    • Computation time was consistently shorter than the gradient duration, confirming real-time capability.
    • Demonstrated imaging feasibility through phantom and in vivo experiments.

    Conclusions:

    • The developed method enables real-time, hardware-compliant gradient waveform design.
    • Significant reductions in computation time and slew-rate overshoot were observed compared to prior methods.
    • This represents the first method for real-time gradient waveform design for arbitrary k-space trajectories.